LC-MS/MS

There’s no stopping the SCIEX Triple Quad LC-MS/MS systems with their modern, robust, and straightforward designs. Known for their accurate quantitation capabilities and Turbo V™ Ion Source, these systems enable scientists to acquire multiple reaction monitoring (MRM), precursor, neutral loss, and product ion scans to develop powerful methods for complex matrices, all while maintaining reproducibility and robustness.

Sciex Triple Quad 6500+ System – The Triple Quad 6500+ LC-MS/MS system features multi-component IonDrive™ technology that pushes the boundaries of quantitation. The sensitivity, speed, and performance delivered through these technology enhancements enable you to see it all, from low mass to high mass compounds.

Sciex Triple Quad 4500 System – The Triple Quad 4500 System takes the API 4000™ platform and intelligently re-engineers it to set a new benchmark for reliable quantitation. Designed for forensics and clinical research.

LC-MS/MS

Enzyme Immunoassay

Immunoassay tests use antibodies to detect the presence of drugs. These tests can be processed rapidly, are inexpensive, and are the preferred initial test for screening. 10 The most commonly ordered drug screens are for cocaine metabolites, amphetamines, phencyclidine, marijuana metabolites, and opiate metabolites.

Immunoassay analyzers are used to identify and detect the concentration of specific substances in a sample, usually using an antibody as a reagent. These devices are used in hospitals and clinical laboratories and can perform a variety of tests including clinical drug testing and more. The AU680 allows us to have scalable immunoassay analyzers and assays, all of which helps optimize our laboratory’s uptime, reliability and performance. The AU680 clinical chemistry analyzer gives mid- to high-volume laboratories the flexibility to improve efficiencies.

SARS-CoV-2 PCR test

The Simplexa® COVID-19 Direct assay targets two different regions of the SARS-CoV-2 genome to provide high sensitivity and help prevent false negatives. A simple workflow with minimal hands on time and results in a little more than an hour allows more efficient test reporting and patient management. The simplicity and flexibility of the LIASION® MDX system, combined with the broad sample coverage of the Simpexa® COVID-19 Direct assay design is a major step towards fighting the COVID-19 pandemic.

Proven performance that you can count on

SIMPLEXA® COVID-19 DIRECT CLINICAL AGREEMENT STUDY

Sample Type Positive % Agreement Negative % Agreement
Nasal Swab 100% (30/30) 100% (30/30)
Nasopharyngeal Swab 100% (52/52) 100% (56/56)

Pharmacogenetics (PgX)

The promise of pharmacogenomics (PGx) is that the use of an individual’s’ genetic information would help to predict drug response and further guide optimal drug and dose selection to enable safer, more effective, and cost-effective treatment.

Targeted genotyping assays probe for preselected variants with well-defined drug-gene interactions. ‘Ready-made’ commercial genotyping assays are often multiplexed PCR-based technologies.

Targeted genotyping assays offer robust interpretation well suited for automation of PGx reporting. The assays typically include well-studied pharmacokinetic and pharmacodynamic markers of the drug metabolizing enzymes (i.e., CYP2D6, CYP2C19, CYP3A5, DPYD, TPMT, and UGT1A1), selected drug transporters (SLCO1B1), receptors (VKORC1), and other genes associated with drug response.

Tecan Fluent 480 Liquid Handling Systems

Gone are the days of hand pipetting where human error can occur. To meet today’s demand for high throughput and accurate results with rapid turnaround time, laboratories look to automated liquid handling systems. The Tecan Fluent 480 fully modular, open architecture allows each instrument to be individually configured with robotic arms for pipetting and labware movement, helping laboratories to meet throughput, cost saving and productivity targets. The Fluent 480 helps the laboratory by benefiting from fast and precise liquid handling automation on a scalable platform with ease operator interaction.

Tecan Fluent 480 Liquid Handling Systems